The Apostle Paul wrote a letter to the Christians at Colossae—known to us as the book of Colossians—which seeks to address some of the challenges of being a follower of Jesus and a proclaimer of his good news in the context of first-century Rome. The ancient nature of this text and its prescriptions for the Colossian church belies the ways that Paul was seeking to subvert the ethos of the empire. Paul’s willingness to undermine the Roman way of life for the sake of the gospel serves as a powerful challenge to twenty-first century subjects of global corporate imperialism.